Medical devices, as well as methods of treatment and manufacturing such devices,are provided for applying vascular therapy locally within the body vessel. Themedical devices (10) include an expandable tubular frame (20) and a sleeve (60).The medical devices can be used for local delivery of a therapeutic agent withina body vessel or a tamponade for a lacerated body vessel, while simultaneouslyallowing perfusion of fluid or blood flow distal of the implanted medical device.The tubular frame of the medical device can have a middle region with a pluralityof members (32). The members can expand radially outward away from a longitudinalaxis of the tubular frame, which can urge the sleeve to contact the wall of the bodyvessel. In the expanded configuration, a portion of the device allows fluid flowto continue while the sleeve is against the body vessel wall.
