Antibody or Fragments that bind to the epitope that specifically binds to a receptor EphA2. Moreover, relates to a conjugate comprising a cytotoxic Agent that is covalently attached to the Antibody and a method for preparing such a conjugate. Pharmaceutical composition, use of Antibody for preparing a Medicine for treating Cancer and a Kit.Claim 1: a Conjugate of an Antibody or a fragment that binds to the epitope according to claims 1 - 4Where such a conjugate comprising a cytotoxic Agent to choose between: a) The maitansinoide formula (1) (b) The maitansinoide formula (2) (c) The maitansinoide formula (3) (d) The maitansinoide formula (4) (e) The maitansinoide formula (5) f the maitansinoide) of formula (6).
