TREATMENT OF CANCER USING A CD33 CHIMERIC ANTIGEN RECEPTOR

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;NOVARTIS AG

发明人:

BROGDON, JENNIFER,EBERSBACH, HILMAR,GILL, SAAR,GLASS, DAVID,HUBER, THOMAS,JASCUR, JULIA,KENDERIAN, SAAD,MANNICK, JOAN,MILONE, MICHAEL, C.,MURPHY, LEON,RICHARDSON, CELESTE,SINGH, RESHMA,SONG, HUIJUAN,W

申请号：

SG11201700416T

公开号：

SG11201700416TA

申请日:

2015.07.21

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors encoding the same, and recombinant T cells comprising the CD33 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD33 binding domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/