Claudio F. Sturino;Claude Dufresne;Julie Farand;Carl Berthelette;Jason Burch;Yongxin Han;Michael Boyd
发明人:
Carl Berthelette,Michael Boyd,Jason Burch,Claude Dufresne,Julie Farand,Yongxin Han,Claudio F. Sturino
申请号:
US13120786
公开号:
US08685999B2
申请日:
2009.09.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention is directed to β-carboline sulphonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, inflammation, osteoarthritis, and rheumatoid arthritis. Pharmaceutical compositions and methods of use are also included.