Wenqing Yao,Jincong Zhuo,Meizhong Xu,Fenglei Zhang,Brian W. Metcalf
申请号:
US14092351
公开号:
US09403775B2
申请日:
2013.11.27
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a compound of Formula I or Formula II:enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula I and II are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.