A system and method for measuring glucose levels in a users blood without having to draw a blood sample. A wave energy source emits wave energy. A resonance chamber is provided that receives the wave energy and produces a frequency oscillation. An opening leads into the resonance chamber that is small yet enables a significant amount of sample tissue to bulge through the opening. The sample tissue of the user is pressed against the opening. At least a portion of the sample tissue passes through the opening and into the resonance chamber. The sample tissue loads the resonance chamber and alters the frequency oscillation created by the resonance chamber. At least some of the altered frequency oscillation is indicative of blood glucose levels within the sample tissue.
