OTERO ESPINAR, FRANCISCO J,ANGUIANO IGEA, M SOLEDAD F,CUTRIN GOMEZ, M ELENA,GOMEZ AMOZA, JOSE LUIS
申请号:
CA2950478
公开号:
CA2950478A1
申请日:
2015.06.03
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention refers to A pharmaceutical composition comprising (i) poloxamer 407, (ii) at least one penetration enhancer, (iii) at least one solubilizing agent selected from the group consisting of cyclodextrins, hydrophilic polymers and mixtures thereof, (iv) at least one biologically active substance, and (v) a vehicle comprising water and a C1-C3 alcohol, or mixtures thereof.