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NOUVEAUX COMPOSÉS POUR INHIBITEURS SÉLECTIFS D'HISTONE DÉSACÉTYLASES ET COMPOSITION PHARMACEUTIQUE LES COMPRENANT
专利权人:
Chong Kun Dang Pharmaceutical Corp.
发明人:
申请号:
EP14792173.8
公开号:
EP2991982B1
申请日:
2014.04.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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