A fusion prosthesis (1) is provided, which is arranged between a first bone structure (2) and a second bone structure (3) to replace bone structure between the first and second bone structures (2, 3) and comprises a prosthesis body (10) and prosthesis fusion surfaces (20, 60) on the prosthesis body (10), wherein the prosthesis fusion surfaces (20, 60) are inosculated with at least one of the first and second bone structures (2, 3) and are provided with microporous structures (30). The prosthesis body (1) is a metal implant of equal size manufactured according to the tomography data, such as CT, MRI, and UCT, of a patient. The prosthesis fusion surfaces (20, 60) are constructed according to the replaced bone structures and are well inosculated with at least one of the first and second bone structures (2, 3). The microporous structures (30) on the prosthesis fusion surfaces (20, 60) are favorable for the crawling and ingrowth of bone cells. After an operation, the prosthesis fusion surfaces (20, 60) of the prosthesis body (1) will be fused with the bone articular surface of at least one of the first and second bone structures (2, 3) to achieve the long-term stability.
