CELLULES DENDRITIQUES DE TYPE AVATAR COMPOSITION DE CHIMIO-IMMUNORADIOTHÉRAPIE À LYMPHOCYTES NK (CELLULES TUEUSES NATURELLES) DIRIGÉS CONTRE LES NÉOANTIGÈNES, INDUISANT UNE MORT CELLULAIRE IMMUNOGÈNE
Contemplated compositions and methods counteract evasive measures of a tumor by rendering access to the tumor microenvironment, tagging the tumor microenvironment with chemoattractant and/or cytokines, delivering or facilitating a cell-based therapy in the tumor microenvironment while providing inhibition of immune suppressor cells in the tumor microenvironment.