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Branched polymers for complex formation with nucleic acids
专利权人:
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
发明人:
GUNATILLAKE PATHIRAJA ARACHCHILLAGE,HINTON TRACEY MICHELLE,THANG SAN,TIZARD MARK LESLIE
申请号:
NZ62799013
公开号:
NZ627990A
申请日:
2013.02.01
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed are branched polymers comprising a support moiety and at least three block co-polymer chains covalently coupled to and extending from the moiety, wherein: (i) each of the at least three block co-polymer chains comprise (a) a cationic polymer block that is covalently coupled to a hydrophilic polymer block, or (b) a cationic polymer block that is covalently coupled to a hydrophobic polymer block, said hydrophobic polymer block being covalently coupled to a hydrophilic polymer block and (ii) at least one of said covalent couplings associated with each of said block co-polymer chains is biodegradable. Also disclosed are branched polymers coupled to a nucleic acid molecule.
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