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Compositions comprising quinazoline derivatives
专利权人:
Jianhui Guo;Haiying He
发明人:
Jianhui Guo,Haiying He
申请号:
US12993629
公开号:
US08507010B2
申请日:
2009.05.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a pharmaceutical composition, useful for the treatment of diseases characterized by abnormal PTKs activity of erbB family in a mammal, comprising pharmaceutically acceptable salts of N-{4-[3-chloro-4-(3-fluoro-benzyloxy) phenylamino]quinazolin-6-yl}-acrylamide, optionally a pharmaceutically applicable carrier or diluent, and a stabilizer having a dispersing and/or protective effect on the active ingredient. The present invention further provides a pharmaceutical formulation comprising said composition, methods for preparation of said composition and said formulation, as well as use of said composition and said formulation for treating diseases characterized by abnormal PTKs activity of erbB family in a mammal.
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