The subject invention relates in part to Cry3Aa in combination with Cry6Aa. The subject invention relates in part to the surprising discovery that combinations of Cry3Aa and Cry6Aa are useful for preventing development of resistance (to either insecticidal protein system alone) by a corn rootworm ( Diabrotica spp.) population. Included within the subject invention are plants producing these insecticidal Cry proteins, which are useful to mitigate concern that a corn rootworm population could develop that would be resistant to either of these insecticidal protein systems alone. Plants (and acreage planted with such plants) that produce these two insecticidal protein systems are included within the scope of the subject invention. The subject invention also relates in part to combinations of Cry3Aa and Cry6Aa proteins "triple-stacked" or "multi-stacked" with another insecticidal protein(s) such as a Cry6Aa protein or binary Cry34/35 proteins. Thus, such embodiments target rootworms with three modes of action. Transgenic plants, including corn, comprising a cry6Aa gene and a cry3Aa gene are included within the scope of the subject invention.本発明は、一つには、Ｃｒｙ３Ａａとの組み合わせでのＣｒｙ３４Ａｂ／３５Ａｂに関する。本発明は、一つには、Ｃｒｙ３４Ａｂ／Ｃｒｙ３５ＡｂとＣｒｙ３Ａａの組み合わせがコーンルートワーム（ジアブロティカ種（Ｄｉａｂｒｏｔｉｃａ ｓｐｐ．））による（いずれかの殺虫タンパク質系のみに対する）抵抗性の発生の予防に有用であるという驚くべき発見に関する。本開示のおかげで当業者には分かるであろうが、これらの殺虫Ｃｒｙタンパク質を生産するトウモロコシ植物は、これらの殺虫タンパク質系のいずれかのみに対して抵抗性であるコーンルートワーム集団が発生し得る懸念の軽減に有用であろう。これら２つの殺虫タンパク質系を生産する植物（及びそのような植物が作付けされた地所）は、本発明の範囲に含まれる。
