A medicinal composition which is in the form of granules, a powder or a preparation for syrup comprising memantine or a pharmaceutically acceptable salt thereof and an enteric polymer, said composition being easy to ingest even for aged people or patients having difficulty in swallowing and showing a reduced bitterness at administration. In particular, granules or a granular preparation for syrup wherein memantine or a pharmaceutically acceptable salt thereof and an enteric polymer are mixed together in granules.一種含有美金剛(memantine)或其藥學上容許鹽及腸溶性聚合物之顆粒劑、散劑或糖漿用劑的醫藥組成物，其即使於高齡者或吞嚥困難的患者亦容易服用，且服藥時之苦味被減少，尤其是顆粒內美金剛或其藥學上容許鹽與腸溶性聚合物係以混合的方式存在的顆粒劑或顆粒狀之糖漿用劑。
