Liqin WANG,Rodrigo LEITE DE OLIVEIRA,Rene BERNARDS
申请号：
US15764781
公开号：
US20180280324A1
申请日:
2016.09.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The current invention relates to treatment of drug resistant melanoma with histone deacetylase inhibitors (HDACi). In particular the invention relates to BRAF and NRAS mutated melanoma and that have acquired resistance to MAPK pathway inhibitors, for example due to previous treatment with such MAPK pathway inhibitors. The invention discloses HDACi and/or MAPK pathway inhibitors for use in such treatment and treatment regimens using such inhibitors.
