Robert H. Gruninger;Peter J. Connolly;Steven K. Wetter;Stuart L. Emanuel;Steven A. Middleton;Shenlin Huang;Ronghui Lin
发明人:
Shenlin Huang,Ronghui Lin,Peter J. Connolly,Stuart L. Emanuel,Steven A. Middleton,Robert H. Gruninger,Steven K. Wetter
申请号:
US12893925
公开号:
US08299082B2
申请日:
2010.09.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
1,2,4-Triazolylaminoaryl(heteroaryl)sulfonamide derivatives of formula (I), pharmaceutically acceptable salts thereof, processes for the manufacture of 1,2,4-triazolylaminoaryl(heteroaryl)sulfonamide derivatives and pharmaceutical compositions containing 1,2,4-triazolylaminoaryl(heteroaryl)sulfonamide derivatives are disclosed:The 1,2,4-triazolylaminoaryl(heteroaryl)sulfonamide derivatives of formula (I) possess cell cycle inhibitory activity and are accordingly useful for their anti cell proliferation (such as anti cancer) activity.