LLC;CALITOR SCIENCES, LLC;CALITOR SCIENCES;SUNSHINE LAKE PHARMA CO., LTD.
发明人:
XI, NING,WANG, LIANG,WANG, TINGJIN
申请号：
CA2920059
公开号：
CA2920059A1
申请日:
2014.09.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the activity of the PI3K enzymes. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of disorders or diseases, such as disorders of immunity and inflammation in which PI3K enzymes play a role in leukocyte function, and hyperproliferative disorders associated with PI3K activity, including but not restricted to leukernias and solid tumors, in mammals, especially humans.
