Clark Rick F.,Curtain Michael L.,Hansen Todd M.,Heyman Howard R.,Mack Helmut,Michaelides Michael,Pliushchev Marina A.,Shah Omar J.,Sorensen Bryan K.,Sweis Ramzi,Tse Chris,Vasudevan Anil,Woller Kevin R.
申请号：
US201514880834
公开号：
US10093624(B2)
申请日:
2015.10.12
申请国别(地区):
美国
年份:
2018
代理人:
Gesicki Glen
摘要：
Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.
