Ning CHEN,Xiaoqi CHEN,Yinhong CHEN,Alan C. CHENG,Richard V. CONNORS,Jeffrey DEIGNAN,Paul John DRANSFIELD,Xiaohui DU,Zice FU,Julie Anne HEATH,Daniel B. HORNE,Jonathan HOUZE,Matthew R. KALLER,Aarif Yusu
申请号:
US15297940
公开号:
US20170042872A1
申请日:
2016.10.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:where the definitions of the variables are provided herein.