The present invention relates to a pharmaceutical combination which may be useful for the treatment of diseases which involve cell proliferation, which involve migration or apoptosis of myeloma cells, which involve angiogenesis or which involve fibrosis. The invention also relates to a method for the treatment of said diseases, comprising simultaneous, separate or sequential administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.本發明係關於可用於治療涉及細胞增殖、涉及骨髓瘤細胞之遷移或凋亡、涉及血管生成或涉及纖維化之疾病的醫藥組合。本發明亦係關於治療該等疾病之方法,其包括以可提供加成性及協同效應之比率同時、分開或依序投與有效量之特定活性化合物及/或與放射療法一起實施共治療,且係關於該等特定化合物及/或放射療法在製造相應醫藥組合製劑中的組合用途。