JACOBSEN, ERIC JON,BLINN, JAMES ROBERT,SPRINGER, JOHN ROBERT,HOCKERMAN, SUSAN L.
申请号：
CA2936551
公开号：
CA2936551A1
申请日:
2015.01.23
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Disclosed herein are substituted pyrrolopyridine and pyrrolopyrazine compounds and compositions useful in the treatment of TAK mediated diseases, such as cancer, having the structure of Formula (I): wherein R1, R2, R3, and R4 are as defined in the detailed description. Methods of modulation of TAK activity in a human or animal subject are also provided, providing therapeutic benefit to subjects with disease conditions, especially cancer.
