Norman, Mark H.,Liu, Longbin,D'Angelo, Noel,Kim, Tae-Seong,Meagher, Kristin,Tamayo, Nuria A.,Smith, Adrian L.,Schenkel, Laurie B.,Xi, Ning,Booker, Shon,Panter, Kathleen,Whittington, Douglas A.,D'Amico,DAngelo, Noel,DAmico,
申请号:
AU2008282728
公开号:
AU2008282728B2
申请日:
2008.08.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention comprises a new class of compounds capable of modulatingthe activity of PI3 kinase and, accordingly, useful for treatment of PI3 kinasemediated diseases, including melanomas, carcinomas and other cancer-relatedconditions. The compounds have a general Formula I wherein each of A,A, A, A, X, R and R aredefined herein. The invention further comprises pharmaceutical compositions,methods for treatment of PI3 kinase mediated diseases, and intermediates andprocesses useful for the preparation of compounds of the invention.