WONG, CHI HUEY,翁启惠,翁啟惠,HSU, TSUI LING,徐翠玲,徐翠玲,LOU, YI WEI,罗翊伟,羅翊偉,LIN, CHIH WEI,林志伟,林志偉,YEH, SHIH CHI,叶士齐,葉士齊,WU, CHUNG YI,吴宗益,吳宗益,WU, HAN CHUNG,吴汉忠,吳漢忠
申请号：
TW104122684
公开号：
TW201627324A
申请日:
2015.07.13
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, lungs, breast, mouse, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervix, ovary, and/or prostate cancer.本文揭示包含結合至SSEA-4之抗體或其抗原結合片段的醫藥組合物,以及其使用方法。使用方法包括(但不限於)癌症療法及診斷學。本揭露之抗體可結合至某些癌細胞表面。本文所揭示之抗體之例示性標靶可包括癌瘤,諸如腦癌、肺癌、乳癌、口腔癌、食道癌、胃癌、肝癌、膽管癌、胰臟癌、結腸癌、腎癌、子宮頸癌、卵巢癌及/或前列腺癌中之癌瘤。
