GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
BAOWEI ZHAO,FENG REN,YINGXIA SANG
申请号：
BR112019015273
公开号：
BR112019015273A2
申请日:
2018.01.19
申请国别(地区):
BR
年份:
2020
代理人:
摘要：
the present invention relates to innovative compounds that inhibit lrrk2 kinase activity, processes for their preparation, compositions containing them and their use in the treatment or prevention of diseases associated or characterized by lrrk2 kinase activity, for example, disease Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).a presente invenção refere-se a compostos inovadores que inibem a atividade de lrrk2 quinase, processos para a sua preparação, a composições contendo os mesmos e a seu uso no tratamento ou prevenção de doenças associadas ou caracterizadas por atividade de lrrk2quinase, por exemplo, doença de parkinson, doença de alzheimer e esclerose lateral amiotrófica (als).
