A method for determining parameters of reaction of a gamma quantum within a scintillation detector of a PET scanner, wherein the signal measured by the scintillator is transformed in at least one photomultiplier into an electric measured signal. The method comprises obtaining an access to a database (130) comprising reference standard signals (W) and reaction parameters assigned to the reference standard signals (W) comparing the measured signal (S) to the reference standard signals (W) and selecting the reference standard signal (W) that best fits the measured signal (S) assigning to the measured signal (S) the reaction parameters assigned to the selected best-fitting reference standard signal (W), as parameters of the reaction of the gamma quantum within the scintillation detector (101) for the measured signal (S) wherein the measured signal (S) and the reference standard signals (W) are represented by points (P) within a generalized measurement space (Ωp) having a number of dimensions (N measurements) being equal to the total number of measurements performed for that gamma quantum.
