#$%^&*AU2019101327A420191212.pdf#####ABSTRACT Provided are an anti-acute myeloid leukemia compound and a preparation method and application thereof The main treatment means for acute myeloid leukemia is still chemotherapy. However, after chemotherapy, the toxic side effects such as myelosuppression, gastrointestinal reactions and cardiotoxicity often occur, which often make patients intolerant. Therefore, how to reduce the side effects of chemotherapy while ensuring the efficacy is a critical clinical problem to be solved. Anew drug A-Z2 for treating acute myeloid leukemia (AML) is provided, which can inhibit a thioredoxin Trx system and exert anti-AML effect, and reduce the toxic side effects produced by chemotherapy drugs at the same time. 1ll
