PROBLEM TO BE SOLVED: To provide a concentration quantification apparatus, a concentration quantification method, and a program capable of noninvasively and accurately quantifying the concentration of target components in an arbitrary layer by accurately measuring and ensuring a close contact state between an irradiation unit and an observation object.SOLUTION: A concentration quantification apparatus 100 according to the present invention comprises: an irradiation part 106 a light reception part 107 an optical path length distribution storage part 103 an optical path length acquisition part 108 a time resolution waveform storage part 105 a close contact determination part 111 for determining whether or not the irradiation part 106 and an observation object is in a close contact state a measurement light intensity acquisition part 113 for, when the close contact determination part 111 determined that the irradiation part 106 and the observation object is in a close contact state, acquiring the intensity of the light received by the light reception part 107 a light absorption coefficient calculation part 117 for calculating the light absorption coefficient of target components of an arbitrary layer and a concentration calculation part 120 for calculating the concentration of the target components of the arbitrary layer on the basis of the light absorption coefficient acquired by the light absorption coefficient calculation part 117.COPYRIGHT: (C)2016,JPO&INPIT【課題】照射部と観測対象との密着状態を、精度良く測定し、確認することで、任意の層における目的成分の濃度を、非侵襲的にかつ精度良く定量することができる濃度定量装置及び濃度定量方法並びにプログラムを提供する。【解決手段】本発明の濃度定量装置100は、照射部106と、受光部107と、光路長分布記憶部103と、光路長取得部108と、時間分解波形記憶部105と、照射部106と観測対象とが密着状態であるか否かを判定する密着判定部111と、密着判定部111が照射部106と観測対象とが密着状態であると判定した場合に、受光部107が受光した光の強度を取得する計測光強度取得部113と、任意の層の目的成分の吸収係数を算出する吸収係数算出部117と、吸収係数算出部117が取得した吸収係数に基づいて任意の層の目的成分の濃度を算出する濃度算出部120とを備えている。【選択図】図1