WILLIAM BOSCH,ELAINE LIVERSIDGE,SUHAS SHELUKAR D.,KAREN THOMPSON
申请号：
HRP20040532
公开号：
HRP20040532B1
申请日:
2004.06.09
申请国别(地区):
HR
年份:
2012
代理人:
摘要：
The present invention relates to a combination of a selective PDE4 inhibitor, as defined herein, and an adrenergic beta2 receptor agonist for simultaneous, sequential or separate administration by the inhaled route in the treatment of an obstructive airways or other inflammatory disease.Nanopartikularni pripravak, naznačen time, da sadr·i spoj 2-(R)-(1-(R)-(3,5-bis(trifluorometil)fenil)etoksi)-3-(S)-(4-fluoro)fenil-4-(3-(5-okso-1H,4H-1,2,4-triazolo)metilmorfolin, ili njegovu farmaceutski prihvatljivu sol, spoj koji na svojoj povr®ini ima apsorbiran barem jedan povr®inski stablilizator u količini dovoljnoj da odr·i efektivnu prosječnu veličinu čestica manjom od oko 1000 nm. Patent sadr·i jo® 14 patentnih zahtjeva.
