Provided are a charged particle beam irradiation system and a charged particle beam irradiation planning method, whereby it is possible to plan the effective irradiation of charged particle beams. This charged particle beam irradiation system (1) is provided with: an irradiation unit (13) for irradiating a tumor (A) with charged particle beams (R) a radiation resistance state measuring unit (21) and a PET device (14) for measuring the radiation resistance state of the tumor (A) a radiation resistance region separating unit (22) for separating the tumor (A) into multiple radiation resistance regions (T1, T2) on the basis of the measuring result of the radiation resistance state a radiation dose computing unit (23) for computing the planned radiation dose amount of the charged particle beams for each radiation resistance region and a radiation plan correcting unit (24) for planning the irradiation of charged particle beams (R) with regard to the tumor (A) on the basis of the computing result of the radiation dose computing unit (23).本發明提供一種能夠計劃有效的帶電粒子線的照射之帶電粒子線照射系統及帶電粒子線照射計劃方法。本發明之帶電粒子線照射系統(1)具備:照射部(13),其對腫瘤(A)照射帶電粒子線(R);放射線耐性狀況測定部(21)及PET裝置(14),測定腫瘤(A)的放射線耐性狀況;放射線耐性區域分割部(22),其基於放射線耐性狀況的測定結果,將腫瘤(A)分割成複數個放射線耐性區域(T1、T2);劑量運算部(23),其按照複數之每個放射線耐性區域,運算帶電粒子線的照射劑量的計劃值;及照射計劃修正部(24),其基於劑量運算部(23)的運算結果,計劃對腫瘤(A)之帶電粒子線(R)的照射。1‧‧‧帶電粒子線照射系統2‧‧‧PET-CT裝置3‧‧‧控制部4‧‧‧放射線耐性狀況測定部5‧‧‧CT圖像拍攝部6‧‧‧照射計劃裝置7‧‧‧放射線耐性區域分割部8‧‧‧劑量運算部9‧‧‧事前照射計劃部Ac‧‧‧加速器L‧‧‧射束傳輸線H‧‧‧建築物
