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PEPTIDE PERMETTANT D'INDUIRE LA RÉGÉNÉRATION D'UN TISSU ET SON UTILISATION
专利权人:
Genomix Co., Ltd.;Osaka University
发明人:
申请号:
EP12777041.0
公开号:
EP2703487A1
申请日:
2012.04.03
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
(Objective) An objective of the present invention is to provide therapeutic agents that, in association with stimulation of PDGFRα-positive cells such as bone marrow mesenchymal stem cells, promote their mobilization into blood and accumulation in a damaged tissue, and induce tissue regeneration in a living body.(Means for solution) Multiple peptides were synthesized, and the migration-promoting activity of each peptide was evaluated. As a result, the present inventors successfully identified multiple peptides that have migration-promoting activity on a PDGFRα-positive bone marrow mesenchymal stem cell line (MSC-1). Further, the present inventors confirmed that the identified peptides also have migration-promoting activity on skin fibroblasts, which are PDGFRα-positive cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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