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NOUVEL ANTICORPS ANTI-PAI-1 HUMAIN
专利权人:
ASTELLAS PHARMA INC.
发明人:
TANAKA, HIROTSUGU,YOSHINO, MASAYASU
申请号:
CA2939897
公开号:
CA2939897A1
申请日:
2015.02.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
[Problem] To provide an anti-human PAI-1 antibody for prevention and treatment of pulmonary fibrosis by binding to active human PAI-1 and inhibiting effects mediated by active human PAI-1. [Solution] The inventors studied anti-PAI-1 antibodies, and provided an anti-human PAI-1 antibody that contains: a heavy-chain variable region comprising the amino acid sequence from amino acid 1 to 118 in SEQ ID No. 2; and a light-chain variable region comprising the amino acid sequence from amino acid 1 to 108 in SEQ ID No. 4.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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