hidroksi H pirolo c benzodiazepin onski derivati kot ključni intermediati za pripravo C substituiranih pirolobenzodiazepinov

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专利权人:

SPIROGEN LIMITED

发明人:

HOWARD PHILIP WILSON,GREGSON STEPHEN JOHN

申请号：

SI200531502

公开号：

SI2270010T1

申请日:

2005.03.01

申请国别(地区):

SI

年份:

2012

代理人:

摘要：

Compounds and method of synthesis of compounds of formula III: and salts, solvates and chemically protected forms thereof, wherein: R 15 is optionally substituted C 1-12 alkyl； R 10 and R 16 together form a double bond between N10 and C11, or R 10 is H and R 16 is OH； R 7 is independently selected from H, R, OH, OR, SH, SR, NH 2 , NHR, NRR', nitro, Me 3 Sn and halo, and the compound is a dimer with each monomer being of formula (III), where the R 8 groups of each monomers form together a dimer bridge.

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中国工程科技知识中心

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http://www.ckcest.cn/home/