Soohyun Kim,Si-Young Lee,Eunsom Kim,Seunghyun Jo,Youngmin Lee,Tania Azam,Suyoung Bae,Areum Kwak,Jaewoo Hong,Hyun Jhung Jhun,Jong Ho Lee,Jungmin Lee,Sulah Youn,Busun Kim
申请号：
US14674590
公开号：
US09669073B2
申请日:
2015.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to a composition for promoting immune activity including a protein selected from the group consisting of dimeric proinsulin, C-peptide partially deleted mutant of dimeric proinsulin, and C-peptide partially deleted mutant of monomeric proinsulin as an effective component and a composition for immunosuppression including C-peptide site of proinsulin as an effective component, and the dimeric proinsulin, the C-peptide partially deleted mutant of dimeric proinsulin, and the C-peptide partially deleted mutant of monomeric proinsulin can be applied as immune enhancers to diabetic patients.
