#$%^&*AU2016266022B220180426.pdf#####Abstract 0 x S (R1 )n R4 A compound of formula (I) R2 (I) wherein X is 0, C=O or S； Y is N or CH； R2 and R4 are each independently H, -(CH 2)pCOOH, -(CH 2)pCON(R 5)2 or -(CH 2)pCOOCi-6alkyl； or R 2 and R4 together form a 6-membered phenyl ring fused to the five membered ring； each R1 is independently selected from H, halo (e.g. fluoro or chloro), C6-1oaryl, C7-12arylalkyl, C2-12 alkenyl； OCl-12 alkyl, OC2-12 alkenyl or a Ci-12 alkyl group； each R5 is H or Ci-6 alkyl； each p is 0 to 3； n is 1 to 4； or a salt, ester, solvate, N-oxide, or prodrug thereof, e.g. a salt thereof. R461R71 1 (GHMattr) P100447 Al J
