SISTEMA TERAPÊUTICO TRANSDÉRMICO PARA ADMINISTRAÇÃO DA SUBSTÂNCIA ACTIVA BUPRENORFINA

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专利权人:

LTS LOHMANN THERAPIE-SYSTEME AG

发明人:

MICHAEL HORSTMANN,THOMAS HILLE,WALTER MULLER

申请号：

PT14169050

公开号：

PT2769714E

申请日:

2007.11.07

申请国别(地区):

PT

年份:

2015

代理人:

摘要：

The therapeutic system has an active substance impermeable rear layer (1), a detention adhesive, and a matrix layer (2) containing an active substance buprenorphine and carboxylic acid i.e. levulinic acid, and a detachable protection layer (3). The matrix layer is formed on the basis of amine-resistant dimethyl polysiloxane or polyisobutylene, where the matrix layer dissolves the buprenorphine in the carboxylic acid. A solution in a form of droplets is dispersed in the matrix layer, which stays in diffusible contact with a polyacrylate layer.

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