TANGY, FREDERIC,BRANDLER, SAMANTHA,DESPRES, PHILIPPE,HABEL, ANDRE
申请号：
CA2884585
公开号：
CA2884585A1
申请日:
2013.09.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to recombinant Measles virus expressing Chikungunya virus polypeptides, and concerns in particular virus like particles (VLP) that contain envelope and capsid proteins of a Chikungunya virus at their surface. These particles are recombinant infectious particles able to replicate in a host after an administration. The invention provides means, in particular nucleic acids, vectors, cells and rescue systems to produce these recombinant infectious particles. The invention also relates to the use of these recombinant infectious particles, in particular under the form of a composition, more particularly in a vaccine formulation, for the treatment or prevention of an infection by Chikungunya virus.
