PROBLEM TO BE SOLVED: To provide a medicine, quasi-drug, or food, which is useful for improving joint flexibility of, for example, shoulder joint, knee joint, or lumbar facet joint or a material or preparation that can be compounded in any of them.SOLUTION: According to the present invention, there is provided a joint flexibility improver comprising as an active ingredient a milk fat globule membrane containing 5 to 100% by mass of phospholipid or 1 to 50% by mass of sphingomyelin. The composition may further comprise as an active ingredient glucosamine or a salt thereof (e.g., 10 to 20000 mg). The dosage form of the composition is a solid preparation for oral administration.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】肩関節、膝関節又は腰椎椎間関節などの関節の柔軟性の向上に有用な医薬品、医薬部外品又は食品、或いはこれらに配合可能な素材又は製剤の提供。【解決手段】乳脂肪球皮膜が、リン脂質を5~100質量%含有し、又はスフィンゴミエリンを1~50質量%含有する、乳脂肪球皮膜を有効成分とする関節の柔軟性向上剤で、更にグルコサミン又はその塩を有効成分(例えば10~20000mg)として含有してもよいもので、剤型が経口投与用の固形製剤である関節の柔軟性向上剤。【選択図】なし
