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POLYAMINE COMPOUNDS TARGETING THE EFFLUX PUMPS OF MULTI-DRUG RESISTANT BACTERIAL PATHOGENS AND METHODS OF USING THE SAME
专利权人:
UNIVERSITY OF SOUTH FLORIDA
发明人:
Renee Fleeman,Radleigh G. Santos,Marcello Angelo Giulianotti,Lindsey Shaw
申请号:
US16397946
公开号:
US20190256452A1
申请日:
2019.04.29
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are efflux pump inhibitors and pharmaceutical compositions comprising the same. The efflux pump inhibitors may be used in methods of preventing antibiotic resistance in a subject, and in methods of treating a bacterial infection in a subject. The efflux pump inhibitor may be co-administered with an antibiotic.
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