The present invention discloses a surgical cement and a manufacturing method thereof. The surgical cement comprises a cementing component selected from the group of a basic calcium phosphate consisting of tetracalcium phosphate, alpha-tricalcium phosphate, decomposed hydroxyapatite, or a combination thereof; a setting reagent selected from the group of an acidic calcium citrate consisting of monocalcium citrate, dicalcium citrate, or a combination thereof; and water; wherein a weight ratio of the cementing component and the setting reagent ranges from about 1:1 to about 8:1. The surgical cement is bioresorbable and bioactive and is useful in orthopedic, maxillofacial, otological and dental applications. In addition, the surgical cement of this invention has a good flow character and a relatively short setting time.本發明係揭露一種外科用骨水泥及其製造方法。此外科用骨水泥包含一骨水泥成分,係選自由磷酸四鈣、α-磷酸三鈣、已分解氫氧基磷灰石或其組合組成之鹼性磷酸鈣的群組中;一固化劑,係選自由檸檬酸一鈣、檸檬酸二鈣或其組合組成之酸性檸檬酸鈣的群組中;以及水。其中骨水泥成分與固化劑的重量比在約1:1至約8:1的範圍。此外科用骨水泥為生物可再吸收且具生物活性,並可適用於骨科、整形外科、頜面、耳科及牙科的應用。此外,本發明中的外科用骨水泥具有良好的流動特性和相對較短的固化時間。