Compounds of formula I and chemicals, methods for their synthesis, compositions containing them, and their use in the treatment of several diseases and disorders, including cognitive disorders associated with CNS diseases and disorders, are described herein.式Iの化合物および化学物質、その合成方法、それらを含む組成物、ならびにCNS疾患および障害と関連する認知障害を含むいくつかの疾患および障害の処置におけるそれらの使用がここに記載される。