#$%^&*AU2020101591A420200910.pdf#####ABSTRACT The invention provides a preparation method of bletilla striata polysaccharide / bioglass temperature sensitive gel and application thereof. The raw material formula of the gel preparation is composed of the main medicinal bletilla striata polysaccharide and the bioactive glass, the temperature-sensitive gel matrix poloxamer, the stabilizer glycerin, the skin absorption promoter DMSO, the preservative hydroxyphenethyl ester and the water for injection. In that invention, the combination of bletilla striata polysaccharide / bioactive glass and the temperature-sensitive in-situ gel is apply to the treatment of diabetic foot ulcer. In addition, that gel is in a liquid state in vitro, and can quickly change into a gel-like semi-solid after bee administered to the ulcer wound surface, so that the drug can be retained on the ulcer surface for a long time. At the same time, combined with the repair effect of bletilla striata polysaccharide and bioactive glass, the purpose of wound healing was achieved.
