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(S)-2-{ [(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino} -propionic acid isopropyl ester
专利权人:
GILEAD PHARMASSET LLC
发明人:
SOFIA, MICHAEL J,DU, JINFA,WANG, PEIYUAN
申请号:
NZ57988008
公开号:
NZ579880A
申请日:
2008.03.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is (S)-2-{ [(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino} -propionic acid isopropyl ester or a stereoisomer thereof such as (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate. Further disclosed is a composition which comprises a compound as defined above and a pharmaceutically acceptable medium for the treatment of a condition that results from an infection by hepatitis C virus, West Nile virus, yellow fever virus, dengue virus, rhinovirus, polio virus, hepatitis A virus, bovine viral diarrhea virus or Japanese encephalitis virus.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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