Ford Daniel James,Huang Qiuya,Neuss Judi Charlotte,Reuberson James Thomas,Vanderhoydonck Bart
申请号:
US201515318422
公开号:
US9969748(B2)
申请日:
2015.06.11
申请国别(地区):
美国
年份:
2018
代理人:
McDonnell Boehnen Hulbert & Berghoff LLP
摘要:
A series of fused bicyclic heteroaromatic derivatives of formula (IA) or (IB), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.