Anti-IL-17A Antibodies

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专利权人:

CLOSED JOINT STOCK COMPANY “BIOCAD”

发明人:

Andrey Borisovich Ulitin,Stanislav Rudolfovich Evdokimov,Valeriy Vladimirovich Soloviev,Yulia Sergeevna Chernyh,Olga Vladimirovna Goncharova,Dmitriy Valerievich Korzhavin,Tatyana Veniaminovna Chernovs

申请号：

US15254225

公开号：

US10442869B2

申请日:

2016.09.01

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The monoclonal IgG-type antibodies were suggested comprising variable domains represented by a combination of VHH-derivative with a variable domain of the light chain VL. Said antibodies can comprise amino acid substitutions at positions 44 and 45 (Kabat numbering) or combinations thereof. Antibodies of the invention possess increased affinity and improved aggregation stability.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/