HANSEN, Hans,LEUNG, Shui-on,QU, Zhengxing,GOLDENBERG, David
申请号:
ES03743421
公开号:
ES2350477T5
申请日:
2003.03.03
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.