GIP上昇抑制剤の評価又は選択方法
- 专利权人:
- 花王株式会社
- 发明人:
- 大崎 紀子,鈴鴨 知佳
- 申请号：
- JP2009231742
- 公开号：
- JP5317919B2
- 申请日:
- 2009.10.05
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a method for evaluating or selecting a GIP-rise inhibitor.
SOLUTION: The method for evaluating on selecting the GIP-rise inhibitor includes the processes (A)-(D), wherein the process (A) is for bringing a substance to be examined into contact with the tissue or cell derived from mammals, capable of developing a CPT1 gene or CPT1 protein or capable of measuring CPT1 enzymatic activity the process (B) for measuring the development amount of the CPT1 gene, development amount of CPT1 protein or CPT1 enzymatic activity in the tissue or cell derived from the mammals the process (C) for comparing the development amount or the enzymatic activity measured in the process (B) with the development amount of the CPT1 gene, development amount of CPT1 protein or CPT1 enzymatic activity, in a reference group which does not make the substance to be examined come into contact with the tissues or the cells derived from mammals, capable of developing the CPT1 gene or CPT1 protein or capable of measuring the CPT1 enzymatic activity and the process (D) for evaluating or selecting the substance to be examined reducing the development amount of the CPT1 gene, development amount of the CPT1 protein or CPT1 enzymatic activity as the GIP-rise inhibitor, on the basis of the result of the process (C).
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- 来源网站：
- 中国工程科技知识中心
