THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
STROBER, SAMUEL,LOWSKY, ROBERT
申请号：
EP14756899
公开号：
EP2961431A4
申请日:
2014.02.07
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to an HLA mismatched recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance.
