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2-acylaminothiazole derivative or salt thereof
专利权人:
ASTELLAS PHARMA INC.
发明人:
Taisuke Takahashi,Takanori Koike,Kenji Negoro,Hiroaki Tanaka,Jun Maeda,Kazuhiro Yokoyama,Hajime Takamatsu
申请号:
US15316645
公开号:
US09951060B2
申请日:
2015.06.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
[Problem]To provide a compound which is useful as an active ingredient for a pharmaceutical composition for preventing or treating urine storage dysfunction, voiding dysfunction, lower urinary tract dysfunction, and the like.[Means for Solution]The present inventors have found that a thiazole derivative substituted with pyrazinylcarbonylamino at the 2-position is an excellent muscarinic M3 receptor-positive allosteric modulator and is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, thereby completing the present invention. 2-Acylaminothiazole derivative or a salt thereof of the present invention is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, for example voiding dysfunction such as underactive bladder.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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