Alf Bjørseth;Johan Moan;Karl E. Gierskcky;Qian Peng;Trond Warloe;Harald Steen
发明人:
Karl E. Gierskcky,Johan Moan,Qian Peng,Harald Steen,Trond Warloe,Alf Bjørseth
申请号:
US12961420
公开号:
US08410172B2
申请日:
2010.12.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22N—CH2COCH2—CH2CO—OR1 (wherein R1 may represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and R2 represents a hydrogen atom or a group R1, and both R2 groups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.