Formulation of sugar solutions for continuous ultracentrifugation for virus purification

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专利权人:

Manfred Reiter

发明人:

Manfred Reiter,Leopold Grillberger,Wolfgang Mundt,Artur Mitterer,Horst Schafhauser

申请号：

US12112191

公开号：

US08969533B2

申请日:

2008.04.30

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention provides a method for purification of a virus or virus antigen comprising providing a virus preparation and centrifugation of said virus preparation in a gradient of a sugar established by the addition of two or more buffered sugar layers of different concentration. The method leads to higher yields and reduces unwanted aggregation of the virus or virus antigen by increasing the volume of the peak pool.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/